Mouse models of lung fibrosis
- Single bleomyocin or silica exposure,
- Lung function analysis by FlexiVent,
- Inflammation (cell differentials, cytokine release),
- Fibronectin and collagen expression,
- Hydroxyproline analysis,
- Masson-Goldner staining.
– Spanjer AI, Baarsma HA, Oostenbrink LM, Jansen SR, Kuipers CC, Lindner M, Postma DS, Meurs H, Heijink IH, Gosens R, Königshoff M. TGF-β-induced profibrotic signaling is regulated in part by the WNT receptor Frizzled-8. FASEB J. 2016;30(5):1823-35.