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The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slicesSeptember 1, 2017 - 12:47 pm
Kistemaker LEM, Oenema TA, Baarsma HA, Bos IST, Schmidt M, Facchinetti F, Civelli M, Villetti G, Gosens R. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L507-L515. Publication: http://www.ncbi.nlm.nih.gov/pubmed/28596292 Abstract Combination therapy of PDE4 inhibitors and anticholinergics induces bronchoprotection in COPD. Mechanical forces that arise during bronchoconstriction may contribute to airway remodeling. Therefore, we investigated […]