The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices

Kistemaker LEM, Oenema TA, Baarsma HA, Bos IST, Schmidt M, Facchinetti…

Anti-inflammatory effects of targeted lung denervation in patients with COPD.

Kistemaker LEM, Slebos DJ, Meurs H, Kerstjens HAM & Gosens…

Tiotropium attenuates IL-13-induced goblet cell metaplasia of human airway epithelial cells.

Kistemaker LEM, Hiemstra PS, Bos IST, Bouwman S, van den Berge…

Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling.

Kistemaker LEM & Gosens R.Trends Pharmacol Sci., 2015 Mar;36(3):164-71. …

Muscarinic M3 receptors contribute to allergen-induced airway remodeling in mice.

Kistemaker LEM, Bos IST, Hylkema MN, Hiemstra PS, Wess J, Meurs…

Bronchoconstriction induces TGF-β release and airway remodeling in guinea pig lung slices.

Oenema TA, Maarsingh H, Smit M, Groothuis GH, Meurs H &…