Elastase-Induced Parenchymal Disruption and Airway Hyper Responsiveness in Mouse Precision Cut Lung Slices: Toward an Ex vivo COPD Model
Van Dijk EM, Culha S, Menzen MH, Bidan CM & Gosens R. Front Physiol. 2017 Jan 4;7:657. Publication: http://www.ncbi.nlm.nih.gov/pubmed/28101062 Abstract Background: COPD is a progressive lung disease characterized by emphysema and enhanced bronchoconstriction. Current treatments focused on bronchodilation can delay disease progression to some extent, but recovery or normalization of loss of lung function is impossible. Therefore, […]